close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
skilSKI-like proto-oncogene a. (783 aa)    
Predicted Functional Partners:
smad3
Mothers against decapentaplegic homolog.
   
 0.831
LOC101074868
MH1 domain-containing protein.
   
 0.831
LOC101072871
Mothers against decapentaplegic homolog.
   
 0.831
SMAD4
Mothers against decapentaplegic homolog.
   
 0.807
LOC101068466
Mothers against decapentaplegic homolog 4-like.
   
 0.807
LOC101072080
Mothers against decapentaplegic homolog.
   
 0.807
ENSTRUP00000076792
annotation not available
   
 0.807
smad9
Mothers against decapentaplegic homolog.
   
 0.716
smad1
Mothers against decapentaplegic homolog.
   
 0.716
LOC101064562
Mothers against decapentaplegic homolog.
   
 0.716
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.