| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CMPK1 | ENSTRUP00000058125 | ENSTRUP00000081632 | ENSTRUP00000058125 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Adenylate/nucleoside-diphosphate kinase. | 0.932 |
| CMPK1 | LOC101076410 | ENSTRUP00000081632 | ENSTRUP00000012574 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase. | 0.951 |
| CMPK1 | LOC101076531 | ENSTRUP00000081632 | ENSTRUP00000029465 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Thymidylate kinase. | 0.616 |
| CMPK1 | ak3 | ENSTRUP00000081632 | ENSTRUP00000026774 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.531 |
| CMPK1 | ak9 | ENSTRUP00000081632 | ENSTRUP00000079788 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Adenylate kinase 9. | 0.961 |
| CMPK1 | cmpk2 | ENSTRUP00000081632 | ENSTRUP00000055300 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | 0.969 |
| CMPK1 | hddc3 | ENSTRUP00000081632 | ENSTRUP00000056278 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | HD domain containing 3. | 0.449 |
| CMPK1 | nme6 | ENSTRUP00000081632 | ENSTRUP00000055535 | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | Nucleoside diphosphate kinase. | 0.934 |
| ENSTRUP00000058125 | CMPK1 | ENSTRUP00000058125 | ENSTRUP00000081632 | Adenylate/nucleoside-diphosphate kinase. | UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. | 0.932 |
| ENSTRUP00000058125 | ITPA | ENSTRUP00000058125 | ENSTRUP00000068546 | Adenylate/nucleoside-diphosphate kinase. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | 0.943 |
| ENSTRUP00000058125 | LOC101076410 | ENSTRUP00000058125 | ENSTRUP00000012574 | Adenylate/nucleoside-diphosphate kinase. | Nucleoside diphosphate kinase. | 0.947 |
| ENSTRUP00000058125 | LOC101076531 | ENSTRUP00000058125 | ENSTRUP00000029465 | Adenylate/nucleoside-diphosphate kinase. | Thymidylate kinase. | 0.962 |
| ENSTRUP00000058125 | ak3 | ENSTRUP00000058125 | ENSTRUP00000026774 | Adenylate/nucleoside-diphosphate kinase. | GTP:AMP phosphotransferase AK3, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. | 0.945 |
| ENSTRUP00000058125 | ak9 | ENSTRUP00000058125 | ENSTRUP00000079788 | Adenylate/nucleoside-diphosphate kinase. | Adenylate kinase 9. | 0.999 |
| ENSTRUP00000058125 | cmpk2 | ENSTRUP00000058125 | ENSTRUP00000055300 | Adenylate/nucleoside-diphosphate kinase. | Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. | 0.962 |
| ENSTRUP00000058125 | hddc3 | ENSTRUP00000058125 | ENSTRUP00000056278 | Adenylate/nucleoside-diphosphate kinase. | HD domain containing 3. | 0.942 |
| ENSTRUP00000058125 | nme6 | ENSTRUP00000058125 | ENSTRUP00000055535 | Adenylate/nucleoside-diphosphate kinase. | Nucleoside diphosphate kinase. | 0.947 |
| ENSTRUP00000058125 | ntpcr | ENSTRUP00000058125 | ENSTRUP00000084284 | Adenylate/nucleoside-diphosphate kinase. | Nucleoside-triphosphatase, cancer-related. | 0.916 |
| ITPA | ENSTRUP00000058125 | ENSTRUP00000068546 | ENSTRUP00000058125 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Adenylate/nucleoside-diphosphate kinase. | 0.943 |
| ITPA | LOC101076410 | ENSTRUP00000068546 | ENSTRUP00000012574 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family. | Nucleoside diphosphate kinase. | 0.961 |