Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2SJJ2_TAKRUBasic helix-loop-helix family, member e23. (227 aa)    
Predicted Functional Partners:
ASCL4
Achaete-scute family bHLH transcription factor 4.
   
 
 0.729
ENSTRUP00000054901
BHLH domain-containing protein.
      
 0.724
LOC101068622
Gamma-aminobutyric acid (GABA) A receptor, subunit alpha 4; Belongs to the ligand-gated ion channel (TC 1.A.9) family.
      
 0.554
vsx1
Visual system homeobox 1 homolog, chx10-like.
   
 
 0.547
ENSTRUP00000058444
BHLH domain-containing protein.
   
 
 0.534
csnk2a2
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
   0.528
LOC101063201
Zgc:86598; Belongs to the protein kinase superfamily.
    
   0.528
LOC101067113
Casein kinase 2, alpha prime polypeptide a; Belongs to the protein kinase superfamily.
    
   0.528
H2S4D3_TAKRU
Casein kinase 2, alpha 4 polypeptide; Belongs to the protein kinase superfamily.
    
   0.528
LOC115250008
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
  
 0.522
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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