cop1 protein (Takifugu rubripes) - STRING interaction network

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cop1

COP1 E3 ubiquitin ligase. (703 aa)

Predicted Functional Partners:

det1

0.992

LOC101079595

0.991

ddb2

0.985

ddb1

0.983

LOC101069856

0.956

ercc8

0.953

LOC101077059

0.953

etv5

0.952

etv1

0.952

stk40

0.948

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101069856	cop1	ENSTRUP00000054777	ENSTRUP00000012618	Tribbles pseudokinase 3.	COP1 E3 ubiquitin ligase.	0.956
LOC101069856	det1	ENSTRUP00000054777	ENSTRUP00000080373	Tribbles pseudokinase 3.	DET1 partner of COP1 E3 ubiquitin ligase.	0.498
LOC101069856	stk40	ENSTRUP00000054777	ENSTRUP00000051931	Tribbles pseudokinase 3.	Serine/threonine kinase 40.	0.953
LOC101077059	LOC101079595	ENSTRUP00000048623	ENSTRUP00000030644	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.830
LOC101077059	cop1	ENSTRUP00000048623	ENSTRUP00000012618	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	COP1 E3 ubiquitin ligase.	0.953
LOC101077059	ddb1	ENSTRUP00000048623	ENSTRUP00000042679	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	Damage-specific DNA binding protein 1.	0.403
LOC101077059	det1	ENSTRUP00000048623	ENSTRUP00000080373	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	DET1 partner of COP1 E3 ubiquitin ligase.	0.485
LOC101079595	LOC101077059	ENSTRUP00000030644	ENSTRUP00000048623	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.830
LOC101079595	cop1	ENSTRUP00000030644	ENSTRUP00000012618	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	COP1 E3 ubiquitin ligase.	0.991
LOC101079595	ddb1	ENSTRUP00000030644	ENSTRUP00000042679	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Damage-specific DNA binding protein 1.	0.622
LOC101079595	ddb2	ENSTRUP00000030644	ENSTRUP00000039019	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Damage-specific DNA binding protein 2.	0.854
LOC101079595	etv1	ENSTRUP00000030644	ENSTRUP00000065895	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ets variant 1.	0.581
cop1	LOC101069856	ENSTRUP00000012618	ENSTRUP00000054777	COP1 E3 ubiquitin ligase.	Tribbles pseudokinase 3.	0.956
cop1	LOC101077059	ENSTRUP00000012618	ENSTRUP00000048623	COP1 E3 ubiquitin ligase.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.953
cop1	LOC101079595	ENSTRUP00000012618	ENSTRUP00000030644	COP1 E3 ubiquitin ligase.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.991
cop1	ddb1	ENSTRUP00000012618	ENSTRUP00000042679	COP1 E3 ubiquitin ligase.	Damage-specific DNA binding protein 1.	0.983
cop1	ddb2	ENSTRUP00000012618	ENSTRUP00000039019	COP1 E3 ubiquitin ligase.	Damage-specific DNA binding protein 2.	0.985
cop1	det1	ENSTRUP00000012618	ENSTRUP00000080373	COP1 E3 ubiquitin ligase.	DET1 partner of COP1 E3 ubiquitin ligase.	0.992
cop1	ercc8	ENSTRUP00000012618	ENSTRUP00000035459	COP1 E3 ubiquitin ligase.	Excision repair cross-complementation group 8.	0.953
cop1	etv1	ENSTRUP00000012618	ENSTRUP00000065895	COP1 E3 ubiquitin ligase.	Ets variant 1.	0.952