Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101063701Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (543 aa)    
Predicted Functional Partners:
APP
Amyloid beta precursor protein.
    
 0.610
LOC101078447
Amyloid-beta A4 protein; Functional neuronal receptor which couples to intracellular signaling pathway through the GTP-binding protein G(O); Belongs to the APP family.
    
 0.610
nrxn1
Neurexin 1b.
   
 0.546
prr12
Proline rich 12a.
      
 0.545
copb1
Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.
      
 0.483
RIC3
RIC3 acetylcholine receptor chaperone.
    
 
 0.468
stk33
Serine/threonine kinase 33; Belongs to the protein kinase superfamily.
      
 0.457
tub
TUB bipartite transcription factor; Belongs to the TUB family.
      
 0.454
psma1
Proteasome subunit alpha type.
      
 0.450
rras2
RAS related 2.
      
 0.438
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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