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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIK5Glutamate ionotropic receptor kainate type subunit 5. (1093 aa)    
Predicted Functional Partners:
GRIK3
Glutamate ionotropic receptor kainate type subunit 3.
  
 
0.623
LOC101079464
Glutamate receptor, ionotropic, kainate 1a.
  
 
0.622
GRIK2-2
Glutamate ionotropic receptor kainate type subunit 2.
  
 
0.621
LOC101073376
Glutamate receptor, ionotropic, kainate 1b.
  
 
0.620
LOC101075174
Glutamate ionotropic receptor kainate type subunit 2.
  
 
0.620
GRIK2
Glutamate ionotropic receptor kainate type subunit 2.
  
 
0.619
LOC497187
Zgc:158846; Belongs to the intermediate filament family.
      
 0.450
LOC101062540
Neuropilin (NRP) and tolloid (TLL)-like 2b.
   
 
 0.434
LOC115250008
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 
 0.400
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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