STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101067852Uncharacterized protein. (678 aa)    
Predicted Functional Partners:
LOC101066292
Uncharacterized protein; Belongs to the protein kinase superfamily.
     
 0.906
LOC101069822
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
     
 0.906
LOC101067856
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
     
 0.906
LOC101080066
Androgen receptor.
  
  
 
0.902
mdm2
MDM2 proto-oncogene.
    
 0.844
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.809
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 
 0.806
LOC101076976
Heat shock protein 90, alpha (cytosolic), class B member 1.
   
 0.785
LOC101069079
Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1.
   
 0.785
ncor2
Nuclear receptor corepressor 2.
    
 0.765
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.