close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cgnCingulin a. (1205 aa)    
Predicted Functional Partners:
ARHGEF2
Rho guanine nucleotide exchange factor 2-like.
     
 0.949
H2U479_TAKRU
Rho/rac guanine nucleotide exchange factor (GEF) 18b.
     
 0.948
LOC101061451
Rho/rac guanine nucleotide exchange factor (GEF) 18a.
     
 0.939
LOC101069449
Tight junction protein 1a; Belongs to the MAGUK family.
   
 
 0.935
LOC101075973
Cingulin b.
  
  
 
0.902
gata4
GATA binding protein 4.
     
  0.900
f11r
F11 receptor, tandem duplicate 1.
   
 
 0.733
LOC101066033
Occludin a.
      
 0.541
arhgef2
Uncharacterized protein.
     
 0.511
ENSTRUP00000073172
annotation not available
     
 0.511
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (24%) [HD]