Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sh3bp5lSH3-binding domain protein 5-like, a. (431 aa)    
Predicted Functional Partners:
sncaip
Synuclein, alpha interacting protein.
    
 
 0.855
telo2
TEL2, telomere maintenance 2, homolog (S. cerevisiae).
      
 0.823
CDH18
Cadherin 18.
      
 0.731
pla2g6
Phospholipase A2, group VI (cytosolic, calcium-independent).
   
  
 0.728
RNF146
Ring finger protein 146.
    
 
 0.674
IKZF5
IKAROS family zinc finger 5.
      
 0.627
LOC101063719
ANTXR cell adhesion molecule 1d.
      
 0.585
LOC101072223
ANTXR cell adhesion molecule 1c.
      
 0.585
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
      
 0.550
LOC101073928
Uncharacterized protein.
    
 
 0.504
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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