Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1166 aa)    
Predicted Functional Partners:
shox2
Short stature homeobox 2.
    
 
 0.694
LOC115253362
Hyperpolarization activated cyclic nucleotide-gated potassium channel 5.
  
  
 
0.558
LOC101061753
Cyclic nucleotide-binding domain-containing protein.
  
  
 
0.555
HCN2
Hyperpolarization activated cyclic nucleotide-gated potassium channel 2b.
  
  
 
0.552
hcn1
Hyperpolarization activated cyclic nucleotide-gated potassium channel 1.
  
  
 
0.552
LOC101073686
Hyperpolarization activated cyclic nucleotide-gated potassium channel 4.
  
  
 
0.549
LOC101064641
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like.
  
  
 
0.547
ENSTRUP00000077882
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like.
  
  
 
0.547
nkx2-5
NK2 homeobox 5.
   
  
 0.516
LOC101071626
T-box transcription factor 18.
      
 0.514
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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