LOC101071600 protein (Takifugu rubripes) - STRING interaction network

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LOC101071600

LON peptidase N-terminal domain and ring finger 1. (596 aa)

Predicted Functional Partners:

rps27a

0.663

uba52

0.639

trip12

0.622

rnf8

0.591

ube2v2

0.583

cul3

0.571

LOC101068996

0.568

LOC101078382

0.568

brca1

0.563

skp1

0.544

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101068996	LOC101071600	ENSTRUP00000042391	ENSTRUP00000013091	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	LON peptidase N-terminal domain and ring finger 1.	0.568
LOC101068996	LOC101078382	ENSTRUP00000042391	ENSTRUP00000071977	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.901
LOC101068996	brca1	ENSTRUP00000042391	ENSTRUP00000050269	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Uncharacterized protein.	0.709
LOC101068996	cul3	ENSTRUP00000042391	ENSTRUP00000024763	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Cullin 3a; Belongs to the cullin family.	0.632
LOC101068996	rnf8	ENSTRUP00000042391	ENSTRUP00000014191	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.937
LOC101068996	rps27a	ENSTRUP00000042391	ENSTRUP00000027679	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ribosomal protein S27a.	0.959
LOC101068996	skp1	ENSTRUP00000042391	ENSTRUP00000019939	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.664
LOC101068996	trip12	ENSTRUP00000042391	ENSTRUP00000016171	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Thyroid hormone receptor interactor 12.	0.928
LOC101068996	uba52	ENSTRUP00000042391	ENSTRUP00000009801	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.953
LOC101068996	ube2v2	ENSTRUP00000042391	ENSTRUP00000056751	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	Ubiquitin-conjugating enzyme E2 variant 2.	0.975
LOC101071600	LOC101068996	ENSTRUP00000013091	ENSTRUP00000042391	LON peptidase N-terminal domain and ring finger 1.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.568
LOC101071600	LOC101078382	ENSTRUP00000013091	ENSTRUP00000071977	LON peptidase N-terminal domain and ring finger 1.	Ubiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family.	0.568
LOC101071600	brca1	ENSTRUP00000013091	ENSTRUP00000050269	LON peptidase N-terminal domain and ring finger 1.	Uncharacterized protein.	0.563
LOC101071600	cul3	ENSTRUP00000013091	ENSTRUP00000024763	LON peptidase N-terminal domain and ring finger 1.	Cullin 3a; Belongs to the cullin family.	0.571
LOC101071600	rnf8	ENSTRUP00000013091	ENSTRUP00000014191	LON peptidase N-terminal domain and ring finger 1.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.591
LOC101071600	rps27a	ENSTRUP00000013091	ENSTRUP00000027679	LON peptidase N-terminal domain and ring finger 1.	Ribosomal protein S27a.	0.663
LOC101071600	skp1	ENSTRUP00000013091	ENSTRUP00000019939	LON peptidase N-terminal domain and ring finger 1.	S-phase kinase-associated protein 1; Belongs to the SKP1 family.	0.544
LOC101071600	trip12	ENSTRUP00000013091	ENSTRUP00000016171	LON peptidase N-terminal domain and ring finger 1.	Thyroid hormone receptor interactor 12.	0.622
LOC101071600	uba52	ENSTRUP00000013091	ENSTRUP00000009801	LON peptidase N-terminal domain and ring finger 1.	Ubiquitin A-52 residue ribosomal protein fusion product 1.	0.639
LOC101071600	ube2v2	ENSTRUP00000013091	ENSTRUP00000056751	LON peptidase N-terminal domain and ring finger 1.	Ubiquitin-conjugating enzyme E2 variant 2.	0.583