Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074664DCN1-like protein. (251 aa)    
Predicted Functional Partners:
cul3
Cullin 3a; Belongs to the cullin family.
   
 0.914
cul5
Cullin 5a; Belongs to the cullin family.
   
 0.907
cul2
Cullin 2; Belongs to the cullin family.
   
 0.886
LOC115248454
RING-box protein 1.
    
 0.863
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.863
cand1
Cullin-associated and neddylation-dissociated 1.
   
 0.827
ube2f
Ubiquitin-conjugating enzyme E2F (putative); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.819
ENSTRUP00000067176
annotation not available
    
 0.819
ube2m
Uncharacterized protein.
    
 0.819
cul4b
Cullin 4B; Belongs to the cullin family.
    
 0.817
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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