Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LOC101066986RasGEF domain family, member 1Bb. (587 aa)    
Predicted Functional Partners:
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 
 0.631
CCNK
Cyclin K; Belongs to the cyclin family.
     
  0.532
haus8
Si:ch211-153a8.4.
      
 0.506
unc5d
Unc-5 netrin receptor Db.
      
 0.488
LOC101069020
Unc-5 netrin receptor Da.
      
 0.488
plk3
Serine/threonine-protein kinase PLK.
      
 0.447
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
  0.408
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6.
    
  0.408
cux2
Homeobox protein cut-like.
   
  
 0.400
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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