Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
traf3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (614 aa)    
Predicted Functional Partners:
tank
TBD domain-containing protein.
    
 0.998
ticam
Toll-like receptor adaptor molecule.
    
 0.996
ikbke
Protein kinase domain-containing protein.
   
 0.992
tradd
Tnfrsf1a-associated via death domain.
    
 0.989
otud5
OTU deubiquitinase 5a.
    
 0.970
ENSTRUP00000005140
TANK-binding kinase 1.
   
 0.966
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
    
 0.966
H2SAI0_TAKRU
Receptor-interacting serine-threonine kinase 2.
   
 0.965
LOC101071639
Interferon regulatory factor 3.
   
 0.964
cd40
CD40.
   
 0.962
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (46%) [HD]