Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mib2Mindbomb E3 ubiquitin protein ligase 2. (1039 aa)    
Predicted Functional Partners:
rps27a
Ribosomal protein S27a.
   
 0.888
prkn
Ubiquitin-like domain-containing protein.
    
 0.886
chmp2b
Charged multivesicular body protein 2Bb.
    
 0.880
ist1
IST1 factor associated with ESCRT-III.
    
 0.875
fau
40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family.
   
 0.871
tradd
Tnfrsf1a-associated via death domain.
    
 0.870
mib1
Mindbomb E3 ubiquitin protein ligase 1.
    
 0.853
LOC101079054
Uncharacterized protein.
   
 0.852
neurl1
Neuralized E3 ubiquitin protein ligase 1Aa.
   
 0.852
neurl1b
Neuralized E3 ubiquitin protein ligase 1B.
   
 0.852
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (26%) [HD]