STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
atad2bATPase family AAA domain containing 2B. (1464 aa)    
Predicted Functional Partners:
LOC101068554
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 
 0.888
ssrp1
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 
 0.874
LOC101075377
Bromo domain-containing protein.
   
 
 0.848
wdr76
WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family.
   
 
 0.794
btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated.
   
 
 0.793
ddb2
Damage-specific DNA binding protein 2.
   
 
 0.793
smarca5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.
   
 
 0.791
H2AZ1
Histone H2A; Belongs to the histone H2A family.
    
 
 0.749
LOC101080230
Histone H2A; Belongs to the histone H2A family.
    
 
 0.749
LOC101062218
Glycerol-3-phosphate dehydrogenase 2 (mitochondrial).
  
 0.744
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.