Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdlim3PDZ and LIM domain 3a. (315 aa)    
Predicted Functional Partners:
pdlim1
PDZ and LIM domain 1 (elfin).
  
  
 
0.901
ENSTRUP00000053253
DUF4749 domain-containing protein.
     
  0.900
ACTN4
Actinin alpha 4.
   
 
 0.758
strbp
Spermatid perinuclear RNA binding protein.
      
 0.701
ENSTRUP00000055710
Ciliary neurotrophic factor.
      
 0.697
LOC101075286
Actinin, alpha 1.
   
 
 0.691
actn3
Actinin alpha 3b.
   
 
 0.690
adcy1
Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
      
 0.636
pdlim5
PDZ and LIM domain 5a.
   
 
0.621
vcl
Vinculin b.
   
 0.602
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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