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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tbx20T-box transcription factor 20. (441 aa)    
Predicted Functional Partners:
nkx2-5
NK2 homeobox 5.
   
 
 0.824
LOC101062944
Homeobox domain-containing protein.
    
   0.752
LOC101067138
Goosecoid.
    
   0.752
H2UEI6_TAKRU
Desmin a; Belongs to the intermediate filament family.
      
 0.653
isl2
ISL LIM homeobox 2a.
    
 
 0.621
gata4
GATA binding protein 4.
   
 
 0.604
phf13
PHD finger protein 13.
    
   0.585
slc25a21
Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family.
    
   0.573
shh
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
      
 0.566
mnx1
Motor neuron and pancreas homeobox 1.
    
 
 0.563
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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