Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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LOC101080087Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1937 aa)    
Predicted Functional Partners:
LOC101077821
Sodium channel, voltage-gated, type I, beta a.
   
 0.960
scn1b
Sodium channel, voltage-gated, type I, beta b.
   
 0.960
LOC101066292
Uncharacterized protein; Belongs to the protein kinase superfamily.
    
  0.930
LOC101069822
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.
    
  0.930
LOC101067856
Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily.
    
  0.930
LOC101068254
Sodium channel, voltage-gated, type IV, beta b.
    
 0.922
LOC101071995
Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2; Belongs to the protein kinase superfamily.
   
 0.913
LOC101068297
Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2.
   
 0.913
H2UVZ3_TAKRU
Protein kinase domain-containing protein.
   
 0.913
ENSTRUP00000061592
annotation not available
  
  
 
0.901
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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