Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rufy2RUN and FYVE domain containing 2. (707 aa)    
Predicted Functional Partners:
rab4a
RAB4a, member RAS oncogene family.
    
 0.915
rufy3
RUN and FYVE domain containing 3.
   
   0.884
LOC101080010
Ras-related protein Rab-33A.
    
 
 0.716
pbld
Phenazine biosynthesis like protein domain containing.
      
 0.637
mbip
MAP3K12 binding inhibitory protein 1.
      
 0.500
H2S9L9_TAKRU
UV radiation resistance associated gene.
    
 
 0.480
H2S4X1_TAKRU
Si:dkey-280e21.3.
      
 0.476
tex10
Testis expressed 10.
     
  0.473
wdr18
WD repeat domain 18.
     
  0.473
itsn1
Intersectin 1 (SH3 domain protein).
    
   0.465
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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