Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dctDopachrome tautomerase. (516 aa)    
Predicted Functional Partners:
slc45a2
Solute carrier family 45 member 2.
      
 0.935
tyrp1
Tyrosinase related protein 1.
  
 
0.913
LOC101069631
Melanocyte inducing transcription factor a.
    
 0.909
asip
Agouti signaling protein 1.
   
  
 0.907
aplp2
Amyloid beta (A4) precursor-like protein 2.
    
 0.895
hps3
Hermansky-Pudlak syndrome 3 protein isoform X1.
      
 0.869
mc1r
Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family.
    
 0.867
oca2
Oculocutaneous albinism II.
      
 0.827
LOC101071427
SRY-box transcription factor 10.
    
 0.799
MITF
Melanocyte inducing transcription factor b.
    
 0.770
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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