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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrasMuscle RAS oncogene homolog. (208 aa)    
Predicted Functional Partners:
shoc2
SHOC2 leucine rich repeat scaffold protein.
    
 0.970
araf
Uncharacterized protein.
   
 0.962
LOC101073008
RAS guanyl releasing protein 4.
    
 0.949
RASGRP2
RAS guanyl releasing protein 2.
    
 0.949
RASGRP1
RAS guanyl releasing protein 1.
    
 0.949
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
   
 0.946
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.945
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.945
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.944
LOC101066488
Ras protein-specific guanine nucleotide-releasing factor 2a.
   
 0.940
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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