Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mrasMuscle RAS oncogene homolog. (208 aa)    
Predicted Functional Partners:
araf
Uncharacterized protein.
    
 0.979
raf1
Uncharacterized protein.
    
 0.979
braf
Uncharacterized protein.
    
 0.979
shoc2
SHOC2 leucine rich repeat scaffold protein.
    
 0.963
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
    
 0.955
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
    
 0.955
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
   
 0.955
LOC101073008
RAS guanyl releasing protein 4.
    
 0.955
RASGRP2
RAS guanyl releasing protein 2.
    
 0.955
RASGRP1
RAS guanyl releasing protein 1.
    
 0.955
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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