Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tmlheTrimethyllysine hydroxylase, epsilon. (434 aa)    
Predicted Functional Partners:
aifm2
Apoptosis inducing factor mitochondria associated 2.
      
 0.891
cdkal1
CDK5 regulatory subunit associated protein 1-like 1.
      
 0.880
LOC101074577
Uncharacterized protein.
      
 0.732
SPRY3
Sprouty RTK signaling antagonist 3.
      
 0.699
apbb1ip
Amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein.
      
 0.646
LOC101079335
Si:dkey-156n14.3.
      
 0.641
slc25a43
Solute carrier family 25 member 43; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.640
CLPB
ClpB homolog, mitochondrial AAA ATPase chaperonin.
   
 
 0.612
fam180a
Uncharacterized protein.
      
 0.611
hadh
Hydroxyacyl-CoA dehydrogenase.
  
 
 0.611
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (48%) [HD]