Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
isoc2Isochorismatase domain containing 2. (197 aa)    
Predicted Functional Partners:
mblac2
Metallo-beta-lactamase domain containing 2.
  
 
 0.895
naprt
Nicotinate phosphoribosyltransferase-like protein.
  
 
 0.869
LOC105416426
Transmembrane protein 86B.
      
 0.783
oplah
5-oxoprolinase, ATP-hydrolysing.
    
 0.770
nit2
Nitrilase family, member 2.
  
 
 0.727
tgfbrap1
Transforming growth factor, beta receptor associated protein 1.
    
   0.697
Nmnat3
Nicotinamide nucleotide adenylyltransferase 3.
    
 0.676
nmnat1
Nicotinamide-nucleotide adenylyltransferase.
    
 0.676
Nmnat2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2.
    
 0.676
LOC101071490
Arginase.
  
 
 0.642
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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