Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
c8bComplement component 8, beta polypeptide. (591 aa)    
Predicted Functional Partners:
LOC101077791
Uncharacterized protein.
    
 0.791
c8g
Complement component 8, gamma polypeptide; Belongs to the calycin superfamily. Lipocalin family.
   
 0.754
itsn1
Intersectin 1 (SH3 domain protein).
    
 0.726
c6
Complement component 6.
   
 
0.690
c8a
Complement component 8, alpha polypeptide.
  
0.661
c9
Complement component C9; Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C9 is the pore-forming subunit of the MAC; Belongs to the complement C6/C7/C8/C9 family.
   
 
0.613
btk
Tyrosine-protein kinase.
    
 0.571
LOC101066455
Complement component 7a.
     
 
0.540
c7
Complement component 7b.
     
 
0.540
masp2
Mannan-binding lectin serine peptidase 2.
      
 0.478
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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