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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frem1Fras1 related extracellular matrix 1a. (2181 aa)    
Predicted Functional Partners:
LOC101068012
FRAS1 related extracellular matrix 2b.
  
0.948
LOC101067303
Integrin beta; Belongs to the integrin beta chain family.
    
  0.902
LOC101061453
Integrin beta; Belongs to the integrin beta chain family.
    
  0.902
itga8
Integrin, alpha 8; Belongs to the integrin alpha chain family.
   
 
  0.901
npnt
Nephronectin a.
    
 0.844
LOC115249042
Uncharacterized protein.
      
 0.645
ANKS1A
Ankyrin repeat and sterile alpha motif domain containing 1A.
   
  0.599
LOC101062574
Fibrillin 2b.
    
 0.599
ENSTRUP00000065203
Si:dkeyp-9d4.3.
   
  0.599
CASKIN1
CASK interacting protein 1.
   
  0.599
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.