dis3l2 protein (Takifugu rubripes) - STRING interaction network

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dis3l2

DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily. (1042 aa)

Predicted Functional Partners:

exosc1

0.961

exosc2

0.956

exosc7

0.954

exosc10

0.954

exosc9

0.952

exosc4

0.949

mtrex

0.948

exosc6

0.948

exosc5

0.944

LOC101066313

0.943

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101066313	dis3l2	ENSTRUP00000058027	ENSTRUP00000015436	Exosome component 3.	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	0.943
LOC101066313	exosc1	ENSTRUP00000058027	ENSTRUP00000073674	Exosome component 3.	Exosome component 1.	0.999
LOC101066313	exosc10	ENSTRUP00000058027	ENSTRUP00000031620	Exosome component 3.	Exosome component 10.	0.997
LOC101066313	exosc2	ENSTRUP00000058027	ENSTRUP00000075662	Exosome component 3.	Exosome component 2.	0.999
LOC101066313	exosc4	ENSTRUP00000058027	ENSTRUP00000051272	Exosome component 3.	Exosome component 4.	0.999
LOC101066313	exosc5	ENSTRUP00000058027	ENSTRUP00000024345	Exosome component 3.	Exosome component 5.	0.999
LOC101066313	exosc6	ENSTRUP00000058027	ENSTRUP00000067574	Exosome component 3.	Exosome component 6.	0.999
LOC101066313	exosc7	ENSTRUP00000058027	ENSTRUP00000020817	Exosome component 3.	Exosome component 7.	0.999
LOC101066313	exosc9	ENSTRUP00000058027	ENSTRUP00000009757	Exosome component 3.	Exosome component 9.	0.999
LOC101066313	mtrex	ENSTRUP00000058027	ENSTRUP00000050676	Exosome component 3.	Mtr4 exosome RNA helicase.	0.992
dis3l2	LOC101066313	ENSTRUP00000015436	ENSTRUP00000058027	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 3.	0.943
dis3l2	exosc1	ENSTRUP00000015436	ENSTRUP00000073674	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 1.	0.961
dis3l2	exosc10	ENSTRUP00000015436	ENSTRUP00000031620	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 10.	0.954
dis3l2	exosc2	ENSTRUP00000015436	ENSTRUP00000075662	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 2.	0.956
dis3l2	exosc4	ENSTRUP00000015436	ENSTRUP00000051272	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 4.	0.949
dis3l2	exosc5	ENSTRUP00000015436	ENSTRUP00000024345	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 5.	0.944
dis3l2	exosc6	ENSTRUP00000015436	ENSTRUP00000067574	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 6.	0.948
dis3l2	exosc7	ENSTRUP00000015436	ENSTRUP00000020817	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 7.	0.954
dis3l2	exosc9	ENSTRUP00000015436	ENSTRUP00000009757	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Exosome component 9.	0.952
dis3l2	mtrex	ENSTRUP00000015436	ENSTRUP00000050676	DIS3-like exonuclease 2; 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase. Essential for correct mitosis, and negatively regulates cell proliferation. Belongs to the RNR ribonuclease family. DIS3L2 subfamily.	Mtr4 exosome RNA helicase.	0.948

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