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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
frkTyrosine-protein kinase. (515 aa)    
Predicted Functional Partners:
Mipol1
Mirror-image polydactyly gene 1 protein isoform X1.
   
  
 0.924
kiaa1328
Zgc:162344.
   
    0.776
LOC101071159
Signal transducing adaptor family member 2b.
    
 0.681
nedd9
Neural precursor cell expressed, developmentally down-regulated 9.
   
 0.678
LOC101074730
Transmembrane phosphatase with tensin homology.
    
 0.661
pten
Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family.
    
 0.661
cd4
T-cell surface glycoprotein CD4.
   
 0.609
matk
Tyrosine-protein kinase.
  
0.583
csk
Tyrosine-protein kinase.
  
0.581
LOC101071528
Macrophage stimulating 1 receptor a.
   
0.579
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.