Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
kptnKaptin (actin binding protein). (438 aa)    
Predicted Functional Partners:
itfg2
Integrin alpha FG-GAP repeat containing 2.
    
 0.999
c18h12orf66
Si:ch211-125a15.1.
  
 
 0.999
nprl2
NPR2 like, GATOR1 complex subunit.
   
 0.992
nprl3
NPR3-like, GATOR1 complex subunit.
    
 0.992
wdr24
WD repeat domain 24.
   
 0.991
wdr59
WD repeat domain 59.
    
 0.990
mios
Missing oocyte, meiosis regulator, homolog (Drosophila).
    
 0.990
depdc5
DEP domain containing 5.
    
 0.988
seh1l
SEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family.
    
 0.988
lamp1
Lysosomal associated membrane protein 1a.
    
 
 0.948
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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