Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC101066985Formin homology 2 domain containing 1. (1347 aa)    
Predicted Functional Partners:
rock2
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.920
LOC101067715
Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity.
    
 0.912
LOC101065208
Usher syndrome 1C.
      
 0.476
LOC101062040
Stabilin 1.
      
 0.476
ENSTRUP00000069727
annotation not available
      
 0.476
ENSTRUP00000053557
Uncharacterized protein.
    
 
 0.464
ENSTRUP00000076236
Uncharacterized protein.
    
 
 0.464
cdc23
CDC23 (cell division cycle 23, yeast, homolog).
    
 
 0.463
mettl3
Methyltransferase like 3; Belongs to the MT-A70-like family.
      
 0.431
MSL3
MSL complex subunit 3.
      
 0.424
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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