Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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gene co-occurrence
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cacna1bVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2372 aa)    
Predicted Functional Partners:
LOC101069694
Calcium channel, voltage-dependent, R type, alpha 1E subunit b.
  
  
 
0.903
cacna1a
Voltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents.
  
  
 
0.902
cacna2d1
Calcium voltage-gated channel auxiliary subunit alpha2delta 1.
   
 0.880
LOC101079089
Calcium channel, voltage-dependent, alpha 2/delta subunit 1a.
   
 0.880
cacna2d2
Calcium channel, voltage-dependent, alpha 2/delta subunit 2a.
   
 0.870
LOC101072949
Calcium channel, voltage-dependent, alpha 2/delta subunit 2b.
   
 0.870
cacnb1
Calcium channel, voltage-dependent, beta 1 subunit.
   
 0.805
LOC101072104
Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 
 0.798
Cacna2d4
VGCC_alpha2 domain-containing protein.
   
 0.790
CACNA2D3
Calcium voltage-gated channel auxiliary subunit alpha2delta 3.
   
 0.790
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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