Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101069230Prostaglandin I2 (prostacyclin) synthase; Belongs to the cytochrome P450 family. (498 aa)    
Predicted Functional Partners:
PTGS1
Prostaglandin-endoperoxide synthase 1.
    
 0.932
LOC101070781
Prostaglandin-endoperoxide synthase 1.
    
 0.932
ptgs2
Prostaglandin-endoperoxide synthase 2b.
    
 0.929
ptges3
Prostaglandin E synthase 3b (cytosolic).
     
 0.925
LOC101068061
Prostaglandin E synthase 3a (cytosolic).
     
 0.925
tbxas1
Thromboxane A synthase 1 (platelet); Belongs to the cytochrome P450 family.
   
 
 0.924
ptges
Prostaglandin E synthase.
   
 
 0.921
ptges2
Prostaglandin E synthase 2-like.
     
 0.915
LOC101063432
Prostaglandin D2 synthase b, tandem duplicate 1; Belongs to the calycin superfamily. Lipocalin family.
     
 0.906
LOC101062110
Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family.
     
  0.900
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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