Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nlkMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (441 aa)    
Predicted Functional Partners:
lef1
Lymphoid enhancer-binding factor 1.
    
 0.995
map3k7
Mitogen-activated protein kinase kinase kinase 7.
    
0.991
LOC101074632
HMG box domain-containing protein.
    
 0.975
tcf7l1
Transcription factor 7 like 1b.
    
 0.975
tcf7l2
Transcription factor 7 like 2.
    
 0.975
LOC115251054
Lymphoid enhancer-binding factor 1-like isoform X1.
    
 0.975
tcf7
Transcription factor 7.
    
 0.975
ENSTRUP00000060126
Transcription factor 7-like 1-C isoform X1.
    
 0.967
foxo3
Forkhead box O3b.
    
 0.917
foxo4
Forkhead box O4.
    
 0.917
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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