Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
raf1Uncharacterized protein. (652 aa)    
Predicted Functional Partners:
map2k2
Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily.
   
0.984
rras2
RAS related 2.
    
 0.984
map2k1
Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily.
   
0.982
LOC101069736
Zgc:55558.
    
 0.981
hras
HRas proto-oncogene, GTPase a.
    
 0.981
mras
Muscle RAS oncogene homolog.
    
 0.979
LOC101079403
Kinase suppressor of ras 1b.
    
0.977
ksr1
Kinase suppressor of ras 1a.
    
0.977
src
Tyrosine-protein kinase.
  
 
0.976
LOC101065281
Tyrosine-protein kinase.
  
 
0.974
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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