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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brinp1Bone morphogenetic protein/retinoic acid inducible neural-specific 1. (759 aa)    
Predicted Functional Partners:
sirt1
Sirtuin 1.
    
 
 0.636
smpdl3a
Acid sphingomyelinase-like phosphodiesterase.
   
  
 0.633
c1h2orf80
Uncharacterized protein C2orf80 homolog.
      
 0.566
wdr35
WD repeat-containing protein 35.
      
 0.526
psme4
Proteasome activator subunit 4a.
      
 0.510
LOC101067416
Neutral sphingomyelinase (N-SMase) activation associated factor.
      
 0.447
astn1
Astrotactin 1.
   
  
 0.417
ppp6c
Serine/threonine-protein phosphatase.
      
 0.402
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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