Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074250RAP1A, member of RAS oncogene family a. (185 aa)    
Predicted Functional Partners:
rapgef1
Rap guanine nucleotide exchange factor (GEF) 1b.
    
 0.980
braf
Uncharacterized protein.
    
 0.978
rapgef6
Rap guanine nucleotide exchange factor (GEF) 6.
    
 0.977
krit1
KRIT1 ankyrin repeat containing.
    
 0.968
LOC101063059
Ras interacting protein 1.
    
 0.942
radil
Ras association and DIL domains.
    
 0.937
H2SYR5_TAKRU
Si:ch73-281f12.4.
    
 0.937
LOC101073575
Mitogen-activated protein kinase.
   
 0.927
LOC101070190
Mitogen-activated protein kinase.
   
 0.927
LOC101078548
Mitogen-activated protein kinase.
   
 0.927
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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