STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ZIC3Zic family member 3. (453 aa)    
Predicted Functional Partners:
TEAD1
TEA domain family member 1b.
    
 0.482
med12
Mediator complex subunit 12.
    
 0.478
rara
Retinoic acid receptor alpha; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The rar/rxr heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 (By similarity); Belongs to the nuclear hormone receptor family. NR1 subfamily.
    
 0.477
nr4a2
Nuclear receptor subfamily 4, group A, member 2b.
    
 
 0.439
rfx4
Regulatory factor X, 4.
    
 
 0.428
ESRRB
Estrogen-related receptor beta.
    
 0.420
NFE2L1
Nuclear factor, erythroid 2 like 1.
      
 0.416
nr2f1
Nuclear receptor subfamily 2, group F, member 1a.
    
 0.413
ripk4
Receptor-interacting serine-threonine kinase 4.
    
 0.403
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.