Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
foxi2Forkhead box i1. (382 aa)    
Predicted Functional Partners:
dlx3
Distal-less homeobox 3b.
    
 
 0.704
fgf3
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 0.649
hinfp
Histone H4 transcription factor.
      
 0.632
plk3
Serine/threonine-protein kinase PLK.
   
 0.581
fbxw11
F-box and WD repeat domain containing 11b.
    
 
 0.556
fgf8
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
    
 0.540
gata3
GATA binding protein 3.
    
 0.533
barx1
BARX homeobox 1.
    
 0.505
HDAC1
Histone deacetylase 1.
   
 0.500
LOC101072042
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 0.500
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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