LOC101063160 protein (Takifugu rubripes) - STRING interaction network

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LOC101063160

Ubiquitin protein ligase E3A. (808 aa)

Predicted Functional Partners:

LOC101079595

0.905

UBE3A

0.901

psmc1

0.867

gsk3b

0.851

ENSTRUP00000085001

0.844

psmd14

0.840

tat

0.828

uchl5

0.821

psmd2

0.820

neurl4

0.815

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000085001	LOC101063160	ENSTRUP00000085001	ENSTRUP00000016582	annotation not available	Ubiquitin protein ligase E3A.	0.844
ENSTRUP00000085001	UBE3A	ENSTRUP00000085001	ENSTRUP00000060593	annotation not available	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.918
LOC101063160	ENSTRUP00000085001	ENSTRUP00000016582	ENSTRUP00000085001	Ubiquitin protein ligase E3A.	annotation not available	0.844
LOC101063160	LOC101079595	ENSTRUP00000016582	ENSTRUP00000030644	Ubiquitin protein ligase E3A.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.905
LOC101063160	UBE3A	ENSTRUP00000016582	ENSTRUP00000060593	Ubiquitin protein ligase E3A.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.901
LOC101063160	gsk3b	ENSTRUP00000016582	ENSTRUP00000080258	Ubiquitin protein ligase E3A.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.851
LOC101063160	neurl4	ENSTRUP00000016582	ENSTRUP00000031967	Ubiquitin protein ligase E3A.	Neuralized E3 ubiquitin protein ligase 4.	0.815
LOC101063160	psmc1	ENSTRUP00000016582	ENSTRUP00000085965	Ubiquitin protein ligase E3A.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.867
LOC101063160	psmd14	ENSTRUP00000016582	ENSTRUP00000043942	Ubiquitin protein ligase E3A.	Proteasome 26S subunit, non-ATPase 14.	0.840
LOC101063160	psmd2	ENSTRUP00000016582	ENSTRUP00000053851	Ubiquitin protein ligase E3A.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.820
LOC101063160	tat	ENSTRUP00000016582	ENSTRUP00000013620	Ubiquitin protein ligase E3A.	Tyrosine aminotransferase; Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate.	0.828
LOC101063160	uchl5	ENSTRUP00000016582	ENSTRUP00000054996	Ubiquitin protein ligase E3A.	Ubiquitin carboxyl-terminal hydrolase.	0.821
LOC101079595	LOC101063160	ENSTRUP00000030644	ENSTRUP00000016582	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin protein ligase E3A.	0.905
LOC101079595	UBE3A	ENSTRUP00000030644	ENSTRUP00000060593	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates.	0.980
LOC101079595	gsk3b	ENSTRUP00000030644	ENSTRUP00000080258	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.	0.785
LOC101079595	neurl4	ENSTRUP00000030644	ENSTRUP00000031967	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Neuralized E3 ubiquitin protein ligase 4.	0.637
LOC101079595	psmc1	ENSTRUP00000030644	ENSTRUP00000085965	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Proteasome 26S subunit, ATPase 1b; Belongs to the AAA ATPase family.	0.619
LOC101079595	psmd14	ENSTRUP00000030644	ENSTRUP00000043942	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Proteasome 26S subunit, non-ATPase 14.	0.641
LOC101079595	psmd2	ENSTRUP00000030644	ENSTRUP00000053851	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.	0.655
LOC101079595	uchl5	ENSTRUP00000030644	ENSTRUP00000054996	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Ubiquitin carboxyl-terminal hydrolase.	0.475