hlx protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

hlx

H2.0-like homeo box 1 (Drosophila). (381 aa)

Predicted Functional Partners:

nup160

0.697

rpl13a

0.624

znf148

0.531

LOC101063819

0.525

IMPDH

0.525

rab20

0.493

esrrg

0.464

LOC101067486

0.464

ESRRB

0.464

tbx21

0.454

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ESRRB	hlx	ENSTRUP00000068882	ENSTRUP00000016589	Estrogen-related receptor beta.	H2.0-like homeo box 1 (Drosophila).	0.464
IMPDH	hlx	ENSTRUP00000069813	ENSTRUP00000016589	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	H2.0-like homeo box 1 (Drosophila).	0.525
IMPDH	rpl13a	ENSTRUP00000069813	ENSTRUP00000073743	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.	0.401
IMPDH	znf148	ENSTRUP00000069813	ENSTRUP00000048402	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Zinc finger protein 148.	0.558
LOC101063819	hlx	ENSTRUP00000035868	ENSTRUP00000016589	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	H2.0-like homeo box 1 (Drosophila).	0.525
LOC101063819	rpl13a	ENSTRUP00000035868	ENSTRUP00000073743	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.	0.401
LOC101063819	znf148	ENSTRUP00000035868	ENSTRUP00000048402	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	Zinc finger protein 148.	0.558
LOC101067486	hlx	ENSTRUP00000024418	ENSTRUP00000016589	Uncharacterized protein.	H2.0-like homeo box 1 (Drosophila).	0.464
esrrg	hlx	ENSTRUP00000003409	ENSTRUP00000016589	Estrogen-related receptor gamma a.	H2.0-like homeo box 1 (Drosophila).	0.464
hlx	ESRRB	ENSTRUP00000016589	ENSTRUP00000068882	H2.0-like homeo box 1 (Drosophila).	Estrogen-related receptor beta.	0.464
hlx	IMPDH	ENSTRUP00000016589	ENSTRUP00000069813	H2.0-like homeo box 1 (Drosophila).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.525
hlx	LOC101063819	ENSTRUP00000016589	ENSTRUP00000035868	H2.0-like homeo box 1 (Drosophila).	Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.	0.525
hlx	LOC101067486	ENSTRUP00000016589	ENSTRUP00000024418	H2.0-like homeo box 1 (Drosophila).	Uncharacterized protein.	0.464
hlx	esrrg	ENSTRUP00000016589	ENSTRUP00000003409	H2.0-like homeo box 1 (Drosophila).	Estrogen-related receptor gamma a.	0.464
hlx	nup160	ENSTRUP00000016589	ENSTRUP00000014391	H2.0-like homeo box 1 (Drosophila).	Nucleoporin 160.	0.697
hlx	rab20	ENSTRUP00000016589	ENSTRUP00000057945	H2.0-like homeo box 1 (Drosophila).	RAB20, member RAS oncogene family.	0.493
hlx	rpl13a	ENSTRUP00000016589	ENSTRUP00000073743	H2.0-like homeo box 1 (Drosophila).	Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.	0.624
hlx	tbx21	ENSTRUP00000016589	ENSTRUP00000032966	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.454
hlx	znf148	ENSTRUP00000016589	ENSTRUP00000048402	H2.0-like homeo box 1 (Drosophila).	Zinc finger protein 148.	0.531
nup160	hlx	ENSTRUP00000014391	ENSTRUP00000016589	Nucleoporin 160.	H2.0-like homeo box 1 (Drosophila).	0.697