Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
VWA5B1Von Willebrand factor A domain containing 5B1. (940 aa)    
Predicted Functional Partners:
rpf2
Ribosome production factor 2 homolog.
   
 
 0.600
grwd1
Glutamate-rich WD repeat containing 1.
   
  
 0.526
noc2l
NOC2-like nucleolar associated transcriptional repressor.
   
  
 0.483
wdr43
WD repeat domain 43.
   
    0.468
H2TBQ8_TAKRU
Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family.
   
   0.466
gtpbp4
Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.
   
  
 0.461
rrp12
Ribosomal RNA processing 12 homolog.
   
    0.458
eed
PWP2 small subunit processome component.
   
    0.456
nle1
Notchless homolog 1 (Drosophila).
   
  
 0.454
sdad1
Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.
   
    0.452
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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