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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plekhg7Pleckstrin homology domain containing, family G (with RhoGef domain) member 7. (722 aa)    
Predicted Functional Partners:
tradd
Tnfrsf1a-associated via death domain.
    
 0.728
tnfa
Tumor necrosis factor alpha.
    
 0.624
LOC101067416
Neutral sphingomyelinase (N-SMase) activation associated factor.
    
 0.555
bag5
BCL2 associated athanogene 5.
    
 0.542
birc6
Baculoviral IAP repeat containing 6.
    
 0.514
LOC101071927
Rho guanine nucleotide exchange factor (GEF) 40.
     
 0.512
optn
Optineurin.
    
  0.492
LOC101069645
Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma.
    
  0.492
madd
MAP-kinase activating death domain.
    
 0.461
wdr81
WD repeat domain 81.
    
 0.428
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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