Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
katna1Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. (483 aa)    
Predicted Functional Partners:
katnb1
Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.
   
 
 0.919
katnbl1
Katanin p80 subunit B-like 1.
   
 
 0.771
LOC105418154
Katanin_con80 domain-containing protein.
   
 
 0.771
aspm
ASH domain-containing protein.
   
 
 0.757
spopl
Speckle type BTB/POZ protein like b.
   
 0.744
LOC101062218
Glycerol-3-phosphate dehydrogenase 2 (mitochondrial).
  
 0.744
SPOP
Speckle type BTB/POZ protein.
   
 0.744
cul3
Cullin 3a; Belongs to the cullin family.
   
 0.721
psmd6
Proteasome 26S subunit, non-ATPase 6.
   
 0.688
psmd12
Proteasome 26S subunit, non-ATPase 12.
   
 0.660
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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