Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fam168aFamily with sequence similarity 168 member A. (226 aa)    
Predicted Functional Partners:
wwp2
E3 ubiquitin-protein ligase.
    
   0.700
ENSTRUP00000070181
annotation not available
    
   0.700
LOC101068611
WW domain containing E3 ubiquitin protein ligase 1.
    
   0.700
recql5
ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily.
    
   0.624
rc3h1
Ring finger and CCCH-type domains 1b.
    
   0.624
polr2g
Polymerase (RNA) II (DNA directed) polypeptide G-like.
    
   0.624
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
    
   0.624
polr2d
Polymerase (RNA) II (DNA directed) polypeptide D.
    
   0.617
ccdc92
Coiled-coil domain containing 92.
      
 0.614
polr2i
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    
   0.558
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (42%) [HD]