Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-expression
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[Homology]
Score
H2SWV4_TAKRURRM domain-containing protein. (486 aa)    
Predicted Functional Partners:
LOC101077689
U2 small nuclear RNA auxiliary factor 1.
   
 0.991
LOC101065658
Uncharacterized protein.
   
 0.991
SUGP1
SURP and G-patch domain containing 1.
    
 0.964
Sf1
Splicing factor 1.
   
 
 0.955
srsf1
Serine and arginine rich splicing factor 1a.
   
 0.953
LOC101066595
Uncharacterized protein.
   
 0.953
sf3b1
Splicing factor 3b, subunit 1.
 
 
 
 0.952
ALYREF
Aly/REF export factor.
   
 0.945
sf3b4
Splicing factor 3b, subunit 4.
   
 
 0.926
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
    
 0.925
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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