Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smc3Structural maintenance of chromosomes protein. (1162 aa)    
Predicted Functional Partners:
smc1a
Structural maintenance of chromosomes protein.
   
0.999
rad21
RAD21 cohesin complex component a.
   
 0.997
LOC101078750
RAD21 cohesin complex component like 1.
   
 0.995
cdca5
Cell division cycle associated 5.
   
 0.993
espl1
Extra spindle pole bodies like 1, separase.
   
 0.992
LOC101076906
Nipped-B protein.
   
 0.990
ENSTRUP00000086694
Rad21_Rec8_N domain-containing protein.
   
 0.989
LOC101062834
Nipped-B protein.
   
 0.984
LOC101067307
Si:ch211-269e2.1.
   
 0.983
stag1
Stromal antigen 1a.
   
 0.983
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (52%) [HD]