STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf6Interferon regulatory factor 6. (520 aa)    
Predicted Functional Partners:
ENSTRUP00000005140
TANK-binding kinase 1.
   
 0.581
LOC101071192
Grainyhead-like transcription factor 3.
   
 
 0.568
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.555
plk3
Serine/threonine-protein kinase PLK.
   
 0.535
ripk4
Receptor-interacting serine-threonine kinase 4.
   
 0.530
traf6
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
   
 0.499
LOC101075171
Interferon regulatory factor.
   
0.491
LOC101071462
Signal transducer and activator of transcription.
   
 0.459
cdc25b
Cell division cycle 25B.
   
 0.457
aen
Interferon stimulated exonuclease gene.
   
 0.448
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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