Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
krt222Keratin 222; Belongs to the intermediate filament family. (530 aa)    
Predicted Functional Partners:
LOC101075370
Hyaluronan synthase 1.
    
 
 0.714
ino80e
INO80 complex subunit E.
   
 0.623
LOC101066100
Keratin 8; Belongs to the intermediate filament family.
   
0.561
cpsf1
Cleavage and polyadenylation specific factor 1.
    
  0.528
cpsf4
Cleavage and polyadenylation specific factor 4.
    
 0.506
LOC101077614
TPR_REGION domain-containing protein.
    
 0.497
cpsf2
Cleavage and polyadenylation specificity factor subunit 2.
    
  0.480
LOC101075419
Cleavage and polyadenylation specific factor 3.
    
  0.480
sympk
Symplekin.
    
  0.472
LOC101077438
Keratin 4; Belongs to the intermediate filament family.
   
  0.465
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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