Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
slc50a1Solute carrier family 50 member 1; Belongs to the SWEET sugar transporter family. (219 aa)    
Predicted Functional Partners:
trappc5
Trafficking protein particle complex subunit 5; May play a role in vesicular transport from endoplasmic reticulum to Golgi.
      
 0.704
krtcap2
Keratinocyte associated protein 2.
   
  
 0.659
slc35c1
Solute carrier family 35 member C1.
      
 0.590
eif3e
Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
      
 0.587
dpm3
Dolichol-phosphate mannosyltransferase subunit 3; Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit to the ER. Belongs to the DPM3 family.
   
  
 0.585
pawr
PRKC, apoptosis, WT1, regulator.
      
 0.519
gosr2
Uncharacterized protein; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network.
      
 0.519
cask
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
      
 0.518
adgrl2
Adhesion G protein-coupled receptor L2a; Belongs to the G-protein coupled receptor 2 family.
      
 0.518
tmed8
Transmembrane p24 trafficking protein 8.
      
 0.516
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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