close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pik3cbPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1098 aa)    
Predicted Functional Partners:
LOC101063692
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.967
pik3r3
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.967
LOC101062512
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.967
LOC101061527
Uncharacterized protein.
    
 0.964
ENSTRUP00000081534
Phosphatidylinositol 3-kinase regulatory subunit beta-like isoform X1.
    
 0.964
pdpk1
3-phosphoinositide dependent protein kinase 1b.
   
 0.958
LOC101069368
Si:ch73-335l21.1.
   
 0.951
LOC101072794
Si:ch211-284e13.4.
   
 0.951
RAC1
Uncharacterized protein.
   
 0.950
LOC101067160
Rac family small GTPase 1b.
   
 0.950
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (30%) [HD]